Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0331344
PubChem CID
N/A (Not available)
Molecular Formula
C16H23F2N3O
Molecular Weight
311.376 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
RKQFSNDFZFVENY-UHFFFAOYSA-N
InChI
InChI=1S/C16H23F2N3O/c1-11-7-14(19-15(22)8-13-9-16(13,17)18)21(20-11)10-12-5-3-2-4-6-12/h7,12-13H,2-...
IUPAC Name
N-(1-(cyclohexylmethyl)-3-methyl-1H-pyrazol-5-yl)-2-(2,2-difluorocyclopropyl)acetamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

22 24 0 0 0 0 0 0 0 0999 V2000
-3.2950 4.5995 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.8883 3.1557 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-3.8172 1...

Experimental Data

Activity Data

Target Ion Channel
Inwardly rectifying subfamily J member 13
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 6030 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.2
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
22
Rotatable Bonds
5
logP
3.7556
Complexity
79.8397
TPSA (Ų)
46.92
H-Bond Donors
1
H-Bond Acceptors
3
Ring Count
3
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